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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ae2602f1d18116905966e4b8e07b4261c872f37dbf3d022d8980555fcbb2d5' 
  AND token = '80YI/RjNluC9Vy0ediywBwD6PG7Ih75X78zGN1GDjL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}