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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8604d9b86d9dcd95223cbeb46d4c5a7c38dd2a49cdb490893f506c29000cec22' 
  AND token = '3XenOxJxyZGIVmmTb+liu8S44KfvcM6+k42Q18NDh4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}