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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34337b43f4a61a7b88c0eaca16dde114d21922c17f155bedf4e1d27b4276dab0' 
  AND token = 'mfFwwJ2sgFLaaEVQTfBQrvOVhsUlgPUXKwofKxXJsxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}