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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb675b6351e28f86eae202b42b2cd0f3308a3bbcb237b01aa3b5f7dde95aac15' 
  AND token = '5YpE2nzcSxgxJOeiJIPm6OdR2UxQko+ocTV9nauQ5JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}