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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf1e1608b228c80a336aba3d1c0fd40a32f3dc7b3a44441084dc3613f84b198' 
  AND token = 'bt/IfyqT456bjdDGnHCkC5+BJksJBW/WvncKpQmuhNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}