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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f142eb15dbd48ddb7ee0263f8b334768d66fe9a42441b0ce5da8520d1b8edde' 
  AND token = 'YgyB6LyXP4bNodW1hmKNwna8a5ysH2+L7ONSpjS1LRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}