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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7355a8fa79a7036c5e8e048aba76920f34330222f88b2656a4e951fbf3aea7cc' 
  AND token = 'x/bSHycOL2KNlzh8cAQW+xvFZvEWQ8VN9MxNw0OLdV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}