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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b39f04a36cd7d01d3db4754d2f48f77b6129cd67ba2c8f00295eb27c3f5774d' 
  AND token = 'SxPaLZTSNE3nvYlx1ZmTzCOl912p5ifV2mPaLsm7pBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}