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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6d186242eb23d024748cb7816454edeb15ed07abc65da5d9ca3baf89b49f8b' 
  AND token = '84Vko2Lv+46C7/k7WEh5x786vFc95PkFSAJssj6gDus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}