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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275ddc0e6b2f2b4801ded14778dbd1888e93014814d3b543f6f03e9bc7450a42' 
  AND token = 'oFN/XXu1ViflEu5llXdRmyB93MZLx8SQri3huFFHf2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}