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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d3c081888a4aea40f621a7b5dc2241985e1014d502b33d406a74202a5d5e7e' 
  AND token = '2R8xond6X2FXDu6tTdBTrqRHhiQep7OHGYDitLxakRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}