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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1b8a0d68c3744d6666240345be8cd5fb8f5d562aebb83569b5f97ed7d70a49' 
  AND token = '8UMMJOx0ai2QOTpKNQZnToyNHX3MzvzKQjaZ2VWh0w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}