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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f5936bf253db1d57347e65b665a4d1c7706c04a99119ad439caf6a586554f8' 
  AND token = '3DqGPeTgW6eS+rIOYHstb5GpB+AWUxpcELYEiY9G2CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}