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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec5c375c52f044ae96b59bb5ae566cd0710b6ff57be7b4a712950b0cc1fe07b' 
  AND token = 'aDACes+hsGW0Ip1ZXYnZmsKcytf430JR7AW02Y8p9zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}