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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434ef13939f9c0be20f2af4cc5b2148e4b0e5da705a702420b36c530e30f86db' 
  AND token = '6oM83h/Aw84Y8MZFxvJ3dHTxG06eHfFDIWVodmUGt9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}