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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14de73cf00852227c4e2f230df48900352bcb442aaa5c230b911d2528e88fd2d' 
  AND token = 'wh5IOaUfkTi2P8u4cQF3p0qDaqR7fmTG9LeheBRQ/fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}