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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730a2be70cf27aa4af4f13c33cf07b648aa4e218274c62c95314ed21fe5255a7' 
  AND token = 'DVUCCST6StajX/J0xdkq/VFwtMqRp/RY1c1ho9q7Ov0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}