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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '511995e0f0f8f14c137c3d1d48ad75a540190806b70eed456de6472c5ee0429b' 
  AND token = 'MYtecvHGGndQUcE13UAzlpMnKA/5m2h3Aw+rG3sw9CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}