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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c81e50881c9b6461d695b3a3b697c0ca3bffd09e78a5d1dce66de1d453e6c7' 
  AND token = 'jeevsAd29rwXRWVrwNS8IEN+GQHl/ZsJFOUPopFg5tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}