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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b992121ec019c58ffb1cf9bb06efde05e9599715cbc5796b49d6c1a2de242866' 
  AND token = 'mlbWRUU13/3Bu8M5LmZIf+QyD9634EZstW5h7cS1fJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}