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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3368ecbea8a797545f1ca92f03e6f1303cf431524a2b4abeb12eefc35bb158' 
  AND token = 'TpEPc8yWfJowG+Qys6b/svdDfW8GBiKFsv52h4+DuC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}