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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24ba32d8c11abe6cbb50577df4fa99cbcb05207a81918565f1f558fe339ab46' 
  AND token = 'xRzYgCkn+aoZRfdcC2PIxIIYY80o+5Dxc8uknY4B3iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}