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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4c36fc1d738c17e82129f396ca1a35f92a243a4658c0e7c85505fa2d6ad945' 
  AND token = 'IVjwC9FZoToe7SQ5ty3Z3KigPX1JqAfOqBNwoqHKASE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}