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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2de143b2da1819515e89a2904c32d351f3dbdd0d9a060a264f52e282bf0d4fb' 
  AND token = 'KFV8pimjnYBlg6LQZ7Tg1I799MBIp1J0w5UPt2ePF24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}