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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eab8516e4e099f91e4e3640323ee49b7b031efe7500b6336d6e6d346d91ed98' 
  AND token = 's4DJ38LtVQujVPoOE0OrIP73gRx4stuaX75eamnOEqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}