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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b22de2183d98ad0a94af99ac61fb67fb5337ae83d8cf73a28916de11e6e8e6b' 
  AND token = 'B/2VSo/BKGnQ12jBBM96CTCGAm9d2lsM+afzfEpKqBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}