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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46d55366f295a0dbccb21a0ab243eb7012774adeea610ad87f7c0e981b98b85' 
  AND token = 'CCkxZcj1VNGsfn7UwE5a0J4CMEtwH4YmTvvy6spy2Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}