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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426a0d570599560b3a85de17d4115e45b2a681dc9f8b5b6bf23cd9844d64fe17' 
  AND token = 'YFYF7S6jGtn+tO4A22bwQx3sPf380trTkS9oTyh+tt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}