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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265f127a76ef4bfd00ca4a4a92f537f75cd5658f08a29ca3a2b7e5810885d0f9' 
  AND token = 'r1EuJH10nE4CiZoiqdtgG1FtC8PZgzrcGf40rMAywIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}