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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc411a6464b5bf81d55e2fcc3363e219f80bca6e110a99dd96b183279e296a29' 
  AND token = '5/QhhnAnK1UMV9Znw81XfsFMtrk451icxWklfB5RiWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}