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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54074c6e7018012dfcafd02f2023820676cd44324cf38a2c66a1eee42f616715' 
  AND token = 'aOWmtgK4ecsTmLbxZd2Lin+iKgUEqQ6x1QeBinFM6Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}