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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eded9ab3fc92fa6358c4368c8cd440026236fb0ff90e25427a531b45250adad8' 
  AND token = 'OkN6p98P8HVrGLhrLjmpbW2b2mSCgxbhWU8/jEH6TX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}