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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27b6700ccc981cb9c40c5c9d4392680515ad379e92b34813c8889cb2889b536' 
  AND token = 'TKpy/MKfgJju47Osw5S5+meXJtftweo2Vdmt2YqOqxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}