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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efa9e052d2c9595d43afa578e54b6fdfc6d4390ad716c8d50260573e48e7a37' 
  AND token = 'nSKQCucqikf0xInj/ip5mlY/HNpC6odDGabwgGSVN60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}