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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e666919f1ef70d53c2e911bfd309fa5a4de6bdf3f06f69192c6a77a32422262e' 
  AND token = '2mJieUvEbgadep6ZuzUBkJrjZg0rVA9VIVUoNCSkiwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}