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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1d9ea6baa1e75dc797ee74447fcf6e4b06e7c2e6836fea7778e97b84c21acc' 
  AND token = '5hUB+pOUSPWmA4G49pjtDuQxa5b7pc0O5ECf2yfigDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}