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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b7482f666588b8b5a19d8de146d4435eb0906baa3e964700599e50e88e680d' 
  AND token = 'E5iC+mTAC6Iqw6fTYOdZUTvL7gSatCoI9g5sp8kfyGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}