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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0041e29ef526ed2db40d104f982a1cdc0107be20fc5c44648c50f3fe8f0f4a9c' 
  AND token = 'wDPy4iqTTys5G3c8hsXX2GYh0olM/ss2/gdb+YR9bno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}