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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e5b2a8ec51a65f7583947fa9ef7a5da66347241453a2f9cad946271ad88b0f' 
  AND token = '6u18GQbExg+7RniUx3EzireN9Na7WkDKGmHpbO2yM+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}