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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef1f3ae529c94dde7264e81ca2475404114d5c421e4f7c7b4cd91f6772ee7a7' 
  AND token = 'MBeIwie+qo+eQB6DUhsjozRGi3zasGsxU9ff4b7FQ5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}