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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6460e85bf198a18232a18d86e5c7ce8db3fdcb8cd8c025a9bec011c9a19a73' 
  AND token = 'lsY4uafYFdV2oAvHpYyyV4PLs9Wa3gbXFKqOY2JPYe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}