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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bd88704202bee6733546af0a941ed5205b64361992a4dcbf8abaec0c32dd5c' 
  AND token = 'DqzZFfosGhSe/+c4J1PX+UDUN7fa/bWo4a6tNs6ME7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}