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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0bb8d7d71f6331757428a7e777c877c319e8321f649b44a34f5a068e4763dc' 
  AND token = 'QWbTKCJapLTCKec09a1OaJkJ3AUhCwl06QEEHzyVO9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}