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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788718aefb4a7c47258c7c90498728969aacdea7c87cb4983a443b90c9a5f0c3' 
  AND token = 'hJM1hOGGO12WQ8lrq6xGSysoT3mdxtBWFL1iD4hj0P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}