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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1377a75e2a5bea325f1ae08358c7590290448454a2dbfccf94c9fcd239350a0' 
  AND token = 'nQN356migqjOv4QDuVIwa1eay8EHISmFqq+v1Aizgf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}