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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f0c7c98759e2bc43307edce4dba8bab9b1016e54d5f83befe6b89c1a6dde6d' 
  AND token = 'TSr4uWJvTLx4uq7Vx4fjkpSKCXWLFtvCQ9Kvw4F0CQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}