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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15511be297497a8bada0c0cf91de6bc999130c6e37a9449f153a7b7a35f71558' 
  AND token = '+JTi5U00MTQtuJJGzjZdhdTHYCUaxpXnGS5iMyq1CFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}