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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ac58d1336924b84a7f0a7950eae75a95866ebc550cf6225c9679df1356b950' 
  AND token = 'wmKZt1KAWYATr1Uhx22xLTbRNth/9lgShtt73MOTKX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}