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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f8cbf0382296a1dad366a49aa6f557f86e90eecbf54ccca53a6c3cf3838814' 
  AND token = 'OT5k74xGZ495w93Y+sAAEH2wAk6nCNMgVQ7+oTiNXU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}