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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd307d54461a6d7f70a680ba6fd67dba6d6dfb15be5f0b43228171a31e97abf06' 
  AND token = 'HesQHoEPNavcYix0y+bpcj2ju4tFCgRBfkPYhI4a4cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}